Full Guidance For Edoxaban
If Creatinine Clearance <15 ml/min:
Not recommended to commence on Edoxaban
If Creatinine Clearance 15 - 50 ml/min:
30mg Once Daily
If Creatinine Clearance over ≥50 ml/min & none of the following: 1) Weight ≤ 60Kg, 2) On certain P-gp Inhibitors (Ciclosporin, Dronedarone, Erythromycin, Ketoconazole)
60mg Once Daily
If Creatinine Clearance over ≥50 ml/min & any of the following: 1) Weight ≤ 60Kg, 2) On certain P-gp Inhibitors (Ciclosporin, Dronedarone, Erythromycin, Ketoconazole)
30mg Once Daily
Please see MedicineMonitoring.com for Edoxaban monitoring requirements.